Individuals using weight-loss injections such as Mounjaro and Wegovy face significant muscle loss if they do not engage in strength training, with some researchers equating this loss to the effects of 10 years of ageing. A recent study highlights that while these drugs effectively reduce fat, they also contribute to lean muscle loss at levels comparable to what is seen following bariatric surgery or during cancer treatment.
The loss of muscle and bone mass associated with these medications can lead to increased frailty and a higher risk of falls among older adults. This is a pressing concern, particularly given that falls contribute to costs of approximately £2.3 billion annually for the NHS. Experts emphasize that integrating exercise—especially strength training—can mitigate muscle loss that frequently accompanies weight loss from these medications.
According to estimates, around 2.5 million people in the United Kingdom are currently using weight-loss drugs. Dr. Matthew Wade, interim director of UKActive, a fitness non-profit organization, stressed the importance of incorporating exercise into treatment plans. “The rapid rollout of GLP-1 has shown dramatic results for patients, but in order to avoid weakening the body, there are simple and effective strength exercises, which are essential for sustainable results,” Dr. Wade stated.
Call for Integrated Support
A report by Les Mills and UKActive advocates for UK gyms to collaborate with the government to develop tailored programs specifically for individuals taking weight-loss medications. Weight-loss injections, categorized as GLP-1 receptor agonists, mimic the natural hormone that regulates blood sugar, appetite, and digestion. This mechanism leads to decreased calorie intake and subsequent weight loss.
Both the NHS and the NICE recommend that weight-loss drugs be complemented with dietary changes and regular exercise. “Regular strength training is vital to our health at all stages of life, but the research suggests this is especially true for people taking weight-loss medications,” said Bryce Hastings, head of research at Les Mills. He further noted that in addition to strength training two to three times a week, those on weight-loss medications should aim for 150 minutes of moderate to vigorous physical activity weekly. This regimen is shown to aid in fat mass loss during the maintenance phase of treatment and reduce the likelihood of weight regain once treatment has concluded.
Hastings acknowledged the need for further research to deepen the understanding of the relationship between weight-loss medications and strength training. Nevertheless, he emphasized that the recommendations outlined in the report provide practical steps to support the growing population utilizing weight-loss drugs.
The potential consequences of neglecting strength training underscore the need for a comprehensive approach to weight management that prioritizes both medication and physical fitness. By encouraging users to actively engage in strength training, healthcare providers can help ensure that patients not only lose weight but also maintain their overall physical strength and health.
