Research from the University of California Los Angeles (UCLA) suggests that certain harmful bacteria found in the guts of infants may increase the likelihood of developing depression in adulthood. This finding highlights the critical connection between gut health and mental well-being, known as the brain-gut axis.
The study, which was published on November 1, 2025, identifies a correlation between specific gut bacteria and mental health outcomes. Researchers found that young children with higher levels of two bacterial strains—clostridiales and lachnospiraceae—were at a greater risk of experiencing anxiety and depression later in life. Both bacterial strains have been previously associated with mental health issues in adults and early childhood adversity, indicating their potential role in shaping stress sensitivity.
Clostridiales bacteria are often ingested through contaminated food or surfaces, particularly improperly cooked meat. In contrast, Lachnospiraceae microbes are integral to the gut microbiome. However, an overabundance of these microbes has been linked to certain autoimmune diseases, raising concerns about their impact on overall health.
Dr. Bridget Callaghan, the lead author of the study, emphasized the importance of understanding the specific species within these bacterial groups. “Our study provides early evidence that gut microbes could help shape mental health during critical school-age years,” Dr. Callaghan stated. She highlighted that with further research, it may be possible to implement changes to the microbiome through interventions such as probiotics or dietary adjustments.
As the understanding of the gut-brain connection deepens, this research opens pathways for preventative measures in mental health care. Identifying harmful bacteria in infants could lead to targeted strategies that promote healthier gut microbiomes, potentially reducing the risk of mental health disorders in future generations.
The implications of this study are significant. By addressing gut health early in life, there may be opportunities to improve mental health outcomes for children as they transition into adulthood. The findings encourage parents and healthcare providers to consider the role of diet and gut health in the overall well-being of infants, paving the way for a more proactive approach to mental health.
